MP26-05 CONSERVATIVE MANAGEMENT FOLLOWING NON-INVASIVE DOWN-STAGING WITH NEOADJUVANT CHEMOTHERAPY FOR MUSCLE-INVASIVE BLADDER CANCER PATIENTS REFUSING RADICAL CYSTECTOMY
نویسندگان
چکیده
منابع مشابه
Efficient delivery of radical cystectomy after neoadjuvant chemotherapy for muscle-invasive bladder cancer: a multidisciplinary approach.
BACKGROUND Cystectomy delay >90 days after a diagnosis of muscle-invasive bladder cancer (MIBC) adversely affects pathologic stage and survival outcomes in patients who undergo primary surgery. After neoadjuvant chemotherapy (NAC), the impact of the timing of cystectomy delivery on these outcomes is uncertain. Poor communication between urologic and medical oncologists can result in cystectomy ...
متن کاملComparison of radical cystectomy with conservative treatment in geriatric (≥80) patients with muscle-invasive bladder cancer.
INTRODUCTION The aim of this study was to compare overall survival in elderly patients (≥ 80 years) with muscle-invasive bladder cancer (MIBC) undergoing either radical cystectomy (RC) or conservative treatment. MATERIAL AND METHODS We performed a retrospective, comparative analysis of overall- and cancer-specific survival in octagenarians with MIBC (≥ pT2) submitted to RC or conservative tre...
متن کامل[Neoadjuvant chemotherapy in muscle-invasive bladder cancer].
Radical cystectomy is the standard treatment for patients with muscle-invasive bladder cancer. Bladder cancer is a chemoresponsive disease and should be dealt with in a multimodality approach. Neoadjuvant chemotherapy is intended for patients with operable clinical stage T2 to T4a muscle-invasive disease to improve survival. Meta-analysis of cisplatin-containing combination neoadjuvant chemothe...
متن کاملOutcome of patients who refuse cystectomy after receiving neoadjuvant chemotherapy for muscle-invasive bladder cancer.
OBJECTIVES To determine the outcome of patients who refuse cystectomy after receiving neoadjuvant chemotherapy for muscle-invasive bladder cancer. METHODS Between 1995 and 2001, 63 patients were evaluated who declined to undergo a planned cystectomy, because they achieved a complete clinical response to neoadjuvant cisplatin-based chemotherapy. Patient, tumor, and treatment features were asse...
متن کاملMulticenter assessment of neoadjuvant chemotherapy for muscle-invasive bladder cancer.
BACKGROUND The efficacy of neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (BCa) was established primarily with methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC), with complete response rates (pT0) as high as 38%. However, because of the comparable efficacy with better tolerability of gemcitabine and cisplatin (GC) in patients with metastatic disease, GC has become ...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2019
ISSN: 0022-5347,1527-3792
DOI: 10.1097/01.ju.0000555670.28860.b9